Researched since 1979, MSM provides the chemical links needed to form and maintain numerous different types of tissues found in the human body, including connective tissue such as articular cartilage. MSM (Methylsulphonylmethane) is a natural form of organic sulfur found in almost all fresh fruits, vegetables, seafood and meat. Food-processing methods may reduce sulfur levels, making supplementation more important than ever. Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, fish, shellfish or tree nut ingredients.