NOW Grape Seed is a highly concentrated natural extract containing a minimum of 90% polyphenols, including OPC's (oligomeric proanthocyanidins), the beneficial antioxidant compounds found in grape seeds. Grape seed extract and OPC's have been the subject of numerous scientific studies demonstrating their efficacy in the support of cardiovascular health and immune system balance. In addition, non-clinical studies have shown that grape seed extract may protect healthy brain and nerve tissues. Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.